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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nuc</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник НЯЦ РК</journal-title><trans-title-group xml:lang="en"><trans-title>NNC RK Bulletin</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1729-7516</issn><issn pub-type="epub">1729-7885</issn><publisher><publisher-name>Национальный ядерный центр Республики Казахстан</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.52676/1729-7885-2021-1-61-67</article-id><article-id custom-type="elpub" pub-id-type="custom">nuc-317</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>РАЗРАБОТКА ПРОГРАММНОГО ОБЕСПЕЧЕНИЯ ДЛЯ РАСЧЁТА ДОЗ ВНУТРЕННЕГО ОБЛУЧЕНИЯ С ИСПОЛЬЗОВАНИЕМ БИОКИНЕТИЧЕСКИХ МОДЕЛЕЙ</article-title><trans-title-group xml:lang="en"><trans-title>DEVELOPEMNT OF SOFTWARE TO CALCUALTE INTERNAL EXPOSURE DOSES USING BIOKINETIC MODELS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Харченко</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kharchenko</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Курчатов</p></bio><bio xml:lang="en"><p>Kurchatov</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шатров</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Shatrov</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Курчатов</p></bio><bio xml:lang="en"><p>Kurchatov</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жамалдинов</surname><given-names>Ф. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhamaldinov</surname><given-names>F. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Курчатов</p></bio><bio xml:lang="en"><p>Kurchatov</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Айдарханов</surname><given-names>А. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Aidarkhanov</surname><given-names>A. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Курчатов</p></bio><bio xml:lang="en"><p>Kurchatov</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Филиал Институт радиационной безопасности и экологии РГП НЯЦ РК<country>Казахстан</country></aff><aff xml:lang="en">Branch Institute of Radiation Safety and Ecology RSE NNC RK<country>Kazakhstan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>01</day><month>05</month><year>2021</year></pub-date><volume>0</volume><issue>1</issue><fpage>61</fpage><lpage>67</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Харченко А.А., Шатров А.Н., Жамалдинов Ф.Ф., Айдарханов А.О., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Харченко А.А., Шатров А.Н., Жамалдинов Ф.Ф., Айдарханов А.О.</copyright-holder><copyright-holder xml:lang="en">Kharchenko A.A., Shatrov A.N., Zhamaldinov F.F., Aidarkhanov A.O.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journals.nnc.kz/jour/article/view/317">https://journals.nnc.kz/jour/article/view/317</self-uri><abstract><p>В данной работе представлен обзор возможностей разработанного программного обеспечения (далее ПО) Bioscheme, а также методика расчета дозы внутреннего облучения на примере биокинетической модели из публикации МКРЗ № 78. По сравнению с существующим на сегодняшний день и применяемым в филиале «ИРБЭ» РГП НЯЦ РК программным обеспечением, ПО Bioscheme позволяет решать не только задачи в рамках существующих биокинетических моделей, но также моделировать и автоматически выводить функции поступления, накопления и выведения радионуклидов для случаев нестандартных.</p></abstract><trans-abstract xml:lang="en"><p>This paper provides a review of developed software capabilities (hereinafter Bioscheme software) as well as a calculation procedure for the internal exposure dose the case of the biokinetic model from an ICRP publication No. 78. Compared to the available software applied by the branch IRSE NNC RK, Bioscheme software allows solution to not only conventional tasks but also simulation and automatic derivation of a function of the intake, accumulation, and decorporation of radionuclides in non-ordinary cases.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>доза внутреннего облучения</kwd><kwd>биокинетические модели</kwd><kwd>система дифференциальных уравнений</kwd><kwd>константа скорости перехода</kwd><kwd>программное обеспечение</kwd></kwd-group><kwd-group xml:lang="en"><kwd>internal exposure dose</kwd><kwd>biokinetic models</kwd><kwd>system of differential equations</kwd><kwd>constant of transfer rate</kwd><kwd>software</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">ICRP report No. 100. 2005. p - 75.</mixed-citation><mixed-citation xml:lang="en">ICRP report No. 100. 2005. p - 75.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">R. 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