nucВестник НЯЦ РКNNC RK Bulletin1729-75161729-7885Национальный ядерный центр Республики Казахстан10.52676/1729-7885-2024-2-50-55nuc-635Research ArticleСтатьиИЗУЧЕНИЕ ЭФФЕКТИВНОСТИ КЕРАМИЧЕСКИХ МЕМБРАН ПРИ ФИЛЬТРАЦИИ ЛЕКАРСТВЕННЫХ ВЕЩЕСТВSTUDYING THE EFFECTIVENESS OF CERAMIC MEMBRANES IN FILTERING PHARMACEUTICALSКамалА.KamalA.

Астана

Astana

arailym.kamal@nu.edu.kzНыгметоваД.NygmetovaD.

Астана

Astana

ЕргельдиновБ.YergeldinovB.

Астана

Astana

СатаеваА.SatayevaA.

ведущий научный сотрудник, доктор биологических наук,

Астана

Astana

aliya.satayeva@nu.edu.kzКимДж.KimJ.

Астана

Astana

ПоулопоулосС.PoulopoulosS.

Астана

Astana

АрхангельскиЕ.ArkhangelskyE.

Астана

Astana

Назарбаев УниверситетКазахстанNazarbayev UniversityKazakhstan202430062024025055Copyright © Камал А., Ныгметова Д., Ергельдинов Б., Сатаева А., Ким Д., Поулопоулос С., Архангельски Е., 20242024Камал А., Ныгметова Д., Ергельдинов Б., Сатаева А., Ким Д., Поулопоулос С., Архангельски Е.Kamal A., Nygmetova D., Yergeldinov B., Satayeva A., Kim J., Poulopoulos S., Arkhangelsky E.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journals.nnc.kz/jour/article/view/635

В данном исследовании проведена оценка эффективности коммерческих керамических мембран (TAMI, Sterilitech, USA) удалять лекарственные вещества из воды. Изучение эффективности проводилось методом фильтрации модельных растворов на основе ультрачистой воды с добавлением сульфаметоксазола и аспирина в концентрации 3 мг/л в течение 3 часов. Данные вещества являются микрозагрязнителями и широко применяются как во всем мире, так и в Казахстане. Анализ остаточных количеств лекарственных веществ в растворе определяли методом высокоэффективной жидкостной хроматографии (ВЭЖХ) до и после окончания эксперимента. Кроме этого, было изучено изменение скорости потока раствора, проходящего через мембрану. Результаты показали 100% удаление аспирина. Однако в отношении сульфаметоксазола выявлено неполное удаление лекарственного вещества (а именно 99,48%). Зафиксировано снижение потока раствора через мембрану с течением времени. Для сульфаметоксазола снижение скорости потока составило с 37 л/м2-ч до 19 л/м2-ч, т.е. почти в два раза. Для аспирина наблюдалось снижение потока с 53 л/м2-ч до 30 л/м2-ч. Это свидетельствует о том, что даже при снижении скорости потока при фильтрации модельного раствора мембрана сохраняет высокую эффективность удалять лекарственные вещества. В целом, полученные результаты свидетельствуют о том, что керамические мембраны имеют потенциал для очистки воды от лекарственных загрязнений.

This study assessed the effectiveness of ceramic membranes in removing drugs from water. The effectiveness was assessed by filtration of model solutions with the addition of sulfamethoxazole and aspirin at a concentration of 3 mg/l. The study of drug concentrations was carried out using high-performance liquid chromatography (HPLC). The results showed 100% and 99.48% removal of aspirin and sulfamethoxazole from the solution, respectively. When filtering model solutions with the addition of medicinal substances, a decrease in the flow of solutions was observed over time and amounted to 19 l/m2-h for sulfamethoxazole and 30 l/m2-h for aspirin, respectively. Overall, the results obtained indicate that ceramic membranes have the potential to purify water from medicinal contaminants.

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The authors declare that there are no conflicts of interest present.